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Kindley note that the COBRA website is under reconstruction.


Cobra Project Description

Persons with HIV on combination antiretroviral therapy (cART) are at increased risk of the premature development of age-associated non-communicable comorbidities (AANCC).
It has therefore been hypothesised that such individuals, despite effective cART, may be prone to accelerated ageing. By building on an established infrastructure for conducting longitudinal HIV cohort studies in Amsterdam and London, the COBRA project provide a detailed, prospective evaluation of AANCC among HIV-infected patients suppressed on cART and appropriately chosen and comparible non-infected controls. The successful execution of the experimental and clinical research outlined in this study will be ensured through a strong interdisciplinary collaboration between clinical, basic and translational scientists bridging the fields of HIV, AANCC and ageing.